UniTS among Italy’s leading universities: ANVUR confirms top tier Read more about UniTS among Italy’s leading universities: ANVUR confirms top tier Immagine Titolo (61).jpg Data notizia Mon, 22/12/2025 - 12:00 Categoria notizia University ateneo Press releases Destinatari canale University Testo notizia The University of Trieste is approaching the end of the year with a result that places it among the small group of Italy’s highest-performing universities: it has been positioned in the top tier of periodic accreditation, receiving a “Fully Satisfactory” institutional judgement from the National Agency for the Evaluation of the University and Research System (ANVUR).In the assessments available to date, the highest judgement has been awarded by ANVUR to only four other Italian universities out of 33 evaluated: University of Pavia, University of Modena and Reggio Emilia (UniMoRe), Politecnico di Torino, and Bocconi University.“I am very proud to share this outcome: UniTS has been placed in the highest evaluation band. It is a third-party, objective assessment that considers the full scope of our activities: teaching, research, public and social engagement, healthcare-related clinical activities, resources and services. It recognises the quality of teamwork that has involved our entire university community,” said Rector Donata Vianelli.In the Agency’s final report, the University of Trieste achieved the top rating in 86.7% of the focus points (20 out of 23), compared with a maximum of 78.3% (18 out of 23) recorded so far by other universities placed in the same band.What periodic accreditation isPeriodic accreditation is the assessment through which ANVUR evaluates, at regular intervals, the overall quality of a university: not only outcomes, but also the processes, procedures and organisation that underpin education, research and third mission/social impact activities, together with resource management and services.Recognised strengthsThe report and the good practices highlighted during the accreditation process point to several distinctive elements. Among the most significant is internationalisation, starting with the substantial share of students from abroad (8% of total enrolments in bachelor’s and master’s degree programmes in academic year 2024/25, one of the highest figures in Italy), and extending to the educational offer that includes double degrees and joint degrees through agreements with European universities. The evaluation also highlights the active involvement of students in decision-making processes and in the quality assurance system, alongside the recognised contribution of technical and administrative staff.In addition, the Agency notes the University’s commitment to teaching innovation, including through the Teaching and Learning Centre (TLC), and the strengthening of technological equipment in classrooms. In research, UniTS has introduced dedicated support for newly hired researchers: a €10,000 starting grant for those who do not have their own funding.The evaluation processThe assessment consisted of document analysis and an on-site visit carried out by an Evaluation Experts Committee (CEV) appointed by ANVUR and composed of academics and students. Degree programmes and doctoral programmes were initially reviewed remotely from 5–7 May 2025; the Committee then visited the University from 20 to 23 May 2025 to extend its assessment.The evaluation covered the University as a whole, a sample of 3 departments (Mathematics, Informatics and Geosciences; Medical, Surgical and Health Sciences; Humanities), 10 first- and second-cycle degree programmes (International Economics and Financial Markets, Physics, Geology, Foreign Languages and Literatures, Law, Medicine and Surgery, Pharmacy, Diplomacy and International Cooperation – Master’s, Computer Engineering – Master’s, Neurosciences – Master’s), and 3 doctoral programmes (Personalised Medicine and Innovative Therapies; Earth Sciences, Fluid Dynamics and Mathematics. Interactions and Methods; Historical, Philosophical and Political-Social Studies).A path of continuous excellenceRector Vianelli emphasised the collective nature of this outstanding result and expressed particular thanks to emeritus Rector Roberto Di Lenarda, under whose leadership the evaluation took place, to his governance team—“first and foremost Prof. Gianpiero Adami”—and to the Quality and Strategic Support Staff Unit, which supported the University throughout this phase.“This excellence judgement,” Vianelli noted, “certifies the robustness of the processes through which UniTS plans, delivers and continuously improves its institutional activities. It strengthens the University of Trieste’s ability to be a reference point for educating students—who in Italy achieve the highest employment rates—for research that is delivering internationally outstanding results, and for social impact through an ongoing dialogue with all local stakeholders, particularly companies, businesses, bodies and institutions. Moreover, success in European calls guarantees the continuous innovation of our infrastructures.“We are very satisfied with the ANVUR judgement,” concluded Vianelli, who has led the University since 1 August. “In Olympic terms, I would say we have won our gold medal”. Abstract Periodic accreditation confirms the top institutional rating, awarded so far to only four of 33 universities. UniTS is the first to achieve the highest mark on 86.7% of the focus points. Rector Vianelli: “A real team result, like winning a gold medal" Mostra nel diario On Periodo di permanenza in Magazine Mon, 22/12/2025 - 12:00 - Sat, 31/01/2026 - 12:00
Rett syndrome: Mirtazapine administered to the first patient Read more about Rett syndrome: Mirtazapine administered to the first patient Immagine Progetto senza titolo (76).png Data notizia Fri, 19/12/2025 - 12:00 Categoria notizia University Press releases Research University and society Destinatari canale University Research Destinatari target Business and Institutions Society Testo notizia After 15 years of research, including three dedicated to the collection of non-profit funding, the MirtaRett project coordinated by Enrico Tongiorgi (UniTS Department of Life Sciences), finally enters clinical practice with the administration of the first therapy to a young patient at the Gaslini Hospital in Genoa.In February 2025, the Italian Pharmaceuticals Agency (AIFA) received the positive opinion of the National Ethics Committee for Paediatric Studies and thus gave the green light to the first worldwide trial on Mirtazapine in Rett Syndrome, a serious neurological disease that affects almost exclusively girls.The clinical study, coordinated by the University of Trieste, will initially extend to 15 young patients and will take place in the main Italian reference hospitals for Rett Syndrome. The trial is fully covered by non-profit funds.The project is supported by the unconditional contribution of Angelini Pharma SpA, Fondazione Canali Onlus, Fondazione Ico Falck and Fondazione Amadei and Setti. In addition to the pharmacological experimentation, the project also provides for the continuous monitoring of patients' vital parameters, such as breathing, heart rate and blood oxygenation. For this purpose, smart T-shirts are used, already distributed to hospitals in Genoa, Siena, Messina and Milan. Originally developed for monitoring athletes, these T-shirts are made of cotton woven with nanofibres capable of detecting the weak electrical signals of the human body and are tailor-made for each patient by the Italian company AccYouRate Group.What is Mirtazapine?Mirtazapine is a commercially available drug, therefore more easily accessible and sustainable. To facilitate its intake, a European company has been identified that can produce it in liquid formulation, a solution that is not widespread since the drug is normally marketed globally as tablets. ‘Our laboratory at UniTS Department of Life Sciences was the first in the world to demonstrate that mirtazapine, despite being an antidepressant, acts on broader mechanisms and can improve breathing, motor control, sleep quality and social communication in patients with Rett’s syndrome,’ explains Prof. Tongiorgi.Access to the trial is open to new patientsIn Friuli Venezia Giulia it is estimated that there are three or four girls affected by the syndrome who are not currently included in the study, but the prospects remain encouraging. ‘We hope that the health facilities in the region will also be able to participate in the trial,’ Tongiorgi said.To ensure the scientific validity of the study, it is necessary to reach a total of 54 patients aged between 5 and 40 years, divided into the ranges 5-10, 11-17 and 18-40 years. Approximately one third have been recruited so the search for new participants is still open. Abstract At Gaslini in Genoa the MirtaRett project has now started: the first worldwide trial on a drug against this serious neurological pathology. The study is coordinated by Enrico Tongiorgi of UniTS Mostra nel diario Off
Fighting discrimination, promoting equal opportunities and wellbeing at study and work places: the CUG Awards Read more about Fighting discrimination, promoting equal opportunities and wellbeing at study and work places: the CUG Awards Immagine WhatsApp Image 2025-12-19 at 11.19.47.jpeg Data notizia Fri, 19/12/2025 - 12:00 Categoria notizia University Press releases University and society Destinatari canale University Destinatari target Enroled students Testo notizia The Equal Opportunities Committee (CUG) awarded the best degree and doctoral theses on fighting all forms of discrimination, promoting equal opportunities and wellbeing at study and work places.The award for the best undergraduate thesis went to Michela Predonzani, who wrote an essay on ‘Inclusive sport as a complementary action in rehabilitation projects aimed at people with intellectual disabilities’.The award for the two best master’s degree thesis went to Jessica Baldassi (Gender certification: Irisiacqua case study) and to Chiara Granato (an adaptive school: a space that creates inclusion).Costanza Ziani was awarded for the best PhD thesis, which was entitled ‘From organisational wellbeing to wellbeing organisation in the public administration’.The variety of themes covered in the theses and the number of applications submitted show that the sensitivity to these issues has grown considerably. This also demonstrate the strategic nature of the path taken by the Equal Opportunities Committee and the entire University in terms of information and training. Abstract The Committee awards prizes for the best degree theses on these topics Mostra nel diario Off
From health emergencies to international mobility: ICL’s top entrepreneurial projects recognised Read more about From health emergencies to international mobility: ICL’s top entrepreneurial projects recognised Immagine ICL-FINALE-web2.jpg Data notizia Wed, 10/12/2025 - 12:00 Categoria notizia University ateneo Press releases University and society Destinatari canale University Study Destinatari target Enroled students Business and Institutions Testo notizia From health emergencies to sustainable everyday shopping, from support for out-of-town students to the wellbeing of pets, all the way to international learning mobility: these are the themes of the five entrepreneurial projects awarded at the Innovators Community Lab 2025 (ICL) final, held in the Sala Cappella of the former Military Hospital in via Fabio Severo.The event concluded the first edition of ICL, which builds on the experience of the University of Trieste’s Contamination Lab.During the final, the 20 finalist projects developed throughout this year’s programme were presented. The five €5,000 scholarships for the best entrepreneurial projects were awarded to: ResQ by Francesco Sulli, a Physics student, who aims to develop a smart first-aid case for companies, schools and public spaces; SiVale by Valentina Malijevic, a Law student, outlining a sustainable, plastic-free supermarket based on reusable and traceable containers; inU by Jovana Obradovic, a Psychology student, a digital platform supporting students in choosing a university and in out-of-town life in Friuli Venezia Giulia; Aura by Asja Feruglio, PhD in Design for Made in Italy—developed in collaboration with Siminozar Bahram, a Business Management student—proposing an advanced solution to reduce odours in dogs, combining scientific method and design; Kansje by Chiara Doga’, a Philosophy student, an app that collects and makes accessible opportunities for training and international mobility for young people.Two training trips were also awarded to Francesco Sulli and Valentina Maljevic, as the best students of the course, enabling them to visit international innovation ecosystems. Overall, the awarded projects and profiles confirm the heterogeneous, multidisciplinary and cosmopolitan character of the ICL cohort, where the exchange of experiences and ideas involved students from different degree programmes and levels—from Physics to Law, from Psychology to Design, Business Management and Philosophy—and from diverse backgrounds.The final also hosted the round table “Training to innovate: the driver of youth entrepreneurship”, bringing together universities, institutions and the business community on the role of education as a driver of innovation. In the discussion, moderated by journalist Paolo Pichierri, Rector Donata Vianelli stressed the importance of creating structured opportunities for dialogue among young people engaged in different academic pathways, pointing to the value of cross-fertilisation between skills and perspectives to support the transition from idea to entrepreneurial project, and highlighting the need to open up to international contexts and networks. The round table also featured Francesca Ros, President of Confindustria Giovani Alto Adriatico, and Giacomo Andolfato, President of Confindustria Giovani Udine.Erik Vesselli, UniTS Delegate for Technology Transfer, added: “The Innovators Community Lab brings together the university’s three missions: education, research and social engagement. Technology transfer becomes tangible when research results enter territories, companies and institutions, also through the creation of new start-ups. This can only happen by working side by side, in a cross-fertilisation process involving lecturers, researchers, female and male students, and representatives of the entrepreneurial ecosystem.”The ICL training programme, now structured to award 6 ECTS credits to those who complete it, further strengthened role-modeling opportunities in this edition, offering examples, experiences and contacts to understand first-hand the dynamics of innovation, enterprise and work through direct engagement with key players from the productive system. Alongside seminars and networking, ICLabbers visited the headquarters of the Marcegaglia Group, where they met the company leadership and toured Casa Marcegaglia, the corporate museum that tells the story, values and vision of a major industrial group.During the evening, the call for the ICL 2025/2026 edition was also presented, with applications open until 12 January 2026. Full information and the call text are available on the University portal.Awarded projects (project profiles)Francesco Sulli, Physics student – “ResQ”ResQ is a smart first-aid case designed to revolutionise emergency management in workplaces, schools and public spaces. It combines certified medical supplies with integrated sensors and a digital interface that guides users step by step, even those without medical training. Through the ResQ Connect app, it monitors the kit’s status, supply expiry dates and intervention history, simplifying the work of H&S officers and safety managers. The project foresees a family of products (Lite, Standard, Pro, Extreme) for contexts ranging from home use to construction sites and extreme outdoor scenarios.Valentina Malijevic, Law student – “SiVale”SiVale, a sustainable supermarketEach year, millions of tonnes of packaging waste come from shopping baskets. Recycling is improving, but it is not enough: the real issue lies in the single-use model. SiVale was created to change this system, positioning itself as a new-generation supermarket. Here, products are sold loose and via refill dispensers, with free use of reusable containers equipped with RFID technology to ensure traceability. Reverse vending machines collect used containers, put them back into circulation and reward customers at the same time. Shopping no longer generates waste, but becomes an act of innovation and environmental responsibility. SiVale shows that a circular, plastic-free and technologically advanced model can become normal, desirable and scalable.Jovana Obradovic, Psychology student – “inU”inU is an independent digital platform that supports students in choosing a university and living as out-of-town students in Friuli Venezia Giulia. It integrates authentic course reviews, peer-to-peer support, detailed local information and a structured partnership with the Regional Guidance Centre (COR) to provide free professional support. With a freemium model and a B2B strategy with local partners, inU aims to become the region’s go-to hub for informed, student-centred university guidance, helping reduce university dropout and enhance the territory.Asja Feruglio, PhD in Design for Made in Italy – “Aura”Project developed with Siminozar Bahram, Business Management studentAura is a research project developing an advanced solution to reduce odours in dogs, ensuring effectiveness, skin safety and biocompatibility. Combining scientific method and design, it delivers a product conceived to improve everyday hygiene and animal wellbeing. Its essence is not merely a fragrance: it represents the bond between dog and human being, a design that translates that relationship into an emotional and identity-based value.Chiara Doga’, Philosophy student – “Kansje”Kansje—Dutch for “small opportunity”—is an app designed for young people who want to pursue training or mobility experiences abroad, even with limited time or financial resources. Many free opportunities, funded by the EU or community-based, remain little known and hard to find: Kansje is the first unified database making them accessible through an intelligent matchmaking system that identifies the most suitable experiences for each user. The app also offers personalised guidance before and after departure, an educational pathway to prepare for travel, and a dedicated forum to connect with other young people. Abstract The Innovators Community Lab final awarded five €5,000 scholarships and two training trips. Applications for the next edition are open until 12 January 2026 Mostra nel diario Off
Melanoma, a ‘deep’ look to predict the risk of metastasis Read more about Melanoma, a ‘deep’ look to predict the risk of metastasis Immagine Titolo (33).jpg Data notizia Thu, 18/12/2025 - 12:00 Categoria notizia University ateneo Destinatari canale University Destinatari target Society Testo notizia Knowing in advance if a melanoma will tend to spread to other organs could become easier thanks to what dermatologists see with a special lens on the skin: the dermatoscope. This is what emerges from an international study just published by Nature Communications, one of the most prestigious scientific journals in the world, in which Prof. Iris Zalaudek (Department of Medical, Surgical and Health Sciences) participated with a research team from the University of Trieste.Today, the risk of melanoma metastases is assessed, especially after the cancer has been removed, by analysing certain characteristics such as thickness and the presence of ulceration under a microscope. These parameters remain fundamental, but they do not always allow to accurately identify patients who will have a recurrence or develop metastases.This is why an international research team coordinated by Aristotle University of Thessaloniki decided to look at another source of information: dermatoscopic images, i.e. ‘enlarged photos’ of melanoma taken before surgery. The study, which involved ten specialist centres on three continents and over 500 patients, collected nearly 800 images. Thirty experienced dermatologists have examined them, describing colours, structures and other visible signs on the lesion in a standardised way.At this point, the researchers put together all the observations and analysed them in relation to the evolution of the disease over time. It turned out that some recurring details in the images really make a difference. When melanoma has extensive ulceration, i.e. areas where the surface of the skin appears ‘broken’, and the so-called ‘blue-white veil’, the risk of metastasis is higher and the likelihood of remaining free of recurrence over time is lower.On the contrary, in cases where the lesion shows very intense pigmentation and signs of regression – small scarring areas indicating a reaction of the immune system against the tumour – the behaviour of the disease tends to be less aggressive, with a lower probability of spreading to other organs.Based on these signs, the international team built three tools to estimate the risk of metastasis: one that uses only dermatoscopic images, one that relies on traditional histological data, and one that combines both information. The most interesting result is that the model based only on the dermatoscope showed a predictive capacity comparable to that of histological parameters. The combination of the two approaches is the best performing.Looking ahead, this means that the dermatoscope – already indispensable for the early detection of melanoma – could also become a tool for estimating the aggressiveness of the tumour in advance, even before surgery. This would allow for more targeted monitoring and more personalised treatment choices, for example to decide who will need additional treatments or closer monitoring.The authors note, however, that this is a retrospective study and that the results will have to be confirmed by new research on even greater numbers of patients before entering clinical practice.Prof. Iris Zalaudek, professor of Cutaneous and Venereal Diseases at UniTS and head of the Department of Dermatology and of the Sexually Transmitted Diseases and HIV centres at the local health services (ASUGI), argues that ‘the results of the study support the notion that the standard in the melanoma treatment must be an accurate clinical and dermoscopic documentation of the first stages. Dermatoscopy has the potential to act as an additional non-invasive prognostic tool for melanoma, providing valuable information on the biological behaviour of the tumour before excision.’‘This approach,’ concludes Zalaudek ‘could improve patient risk stratification and support decision-making on adjuvant and neoadjuvant treatments’. Abstract Prof. Zalaudek (DSM) in an international study published by Nature Communications Mostra nel diario Off
Less noisy and more sustainable ships: DIA participates in the project ‘Acoustic Black Holes - SilentShip’ Read more about Less noisy and more sustainable ships: DIA participates in the project ‘Acoustic Black Holes - SilentShip’ Immagine Titolo (32).jpg Data notizia Wed, 17/12/2025 - 12:00 Categoria notizia University ateneo Research Destinatari canale University Research Destinatari target Business and Institutions Testo notizia Improve comfort on board, resetting the vibro-acoustic footprint to protect the marine environment and ensure the wellbeing of passengers and crew. These are the ambitious objectives that kicked off the research and development project ‘SilentShip - Acoustic Black Holes, a new frontier for silent ships’.The initiative, strategic and co-financed by the Regional ERDF Programme of the Friuli Venezia Giulia Region, sees the Department of Engineering and Architecture (DIA) of the University of Trieste as a scientific partner, alongside industrial leaders such as Fincantieri and Esteco, with the management support of MareFVG. The project leader is Consorzio Servizi Navali e Industriali - CSNI.The key to innovation lies in Acoustic Black Holes (ABH), devices based on a particular geometry and applied to parts of the structures. In practice, these geometries cause vibrations to ‘concentrate’ there: mechanical energy slows down and is more easily dissipated by dedicated materials or treatments. This is why ABHs are described as real ‘wells’ of vibrational energy. The use of this technology makes it possible to design light and sustainable solutions to limit the propagation of vibrations generated by the main machinery and, consequently, to contain the noise perceived on board and radiated outwards.Within the project, the Department of Engineering and Architecture will play a crucial role ranging from theory to experimentation. The research team is led by Giada Kyaw Oo D'Amore, junior researcher at DIA, as scientific project manager and UniTS coordinator and includes Prof. Marco Biot, Prof. Mitja Morgut and Giovanni Rognoni, research assistant at DIA.UniTS researchers will focus on developing advanced numerical models and performing complex simulations aimed at identifying the most effective ABH geometries and the essential parameters to optimise them. These analyses will also produce useful guidelines to establish where to place prototypes on naval structures to obtain the maximum effect.The research group will also provide a fundamental contribution in the validation phase, in fact it will design and conduct progressive tests, from the laboratory to naval mock-ups, up to the tests on board the ship. These activities will be used to detect the real stresses that vibrations generate, so as to insert them accurately in numerical models. Tests will also be used to verify the effectiveness of the solutions identified on the computer and to refine the prototypes, ensuring that the expected performance in simulation is confirmed even under operational conditions.Finally, the commitment of the DIA will extend to sustainability and open innovation aspects. The team will carry out Life Cycle Assessments (LCA) of the developed product and will conduct studies to apply Open Innovation solutions consistent with the philosophy of Company 5.0, in which technological progress is oriented both towards improving quality of life and reducing environmental impacts. The Department will also contribute to the definition of the technical specifications of the product and the production process.The ‘SilentShip’ project has a total funding of € 1,366,685.17, with a regional contribution of € 822,016.20 and EU co-financing of € 328,806.48. The budget available to the UniTS team amounts to € 418 130.20, confirming the importance of the research work carried out by researchers at the University of Trieste.With a duration of 42 months, the project aims to set a new technological frontier in the naval sector, making vessels not only more comfortable for humans, but also more respectful of the marine environment. Abstract The UniTS team is a partner of CSNI, Fincantieri and Esteco: develop numerical models and experimental tests to reduce vibration and noise on board, with attention to sustainability and open innovation Mostra nel diario Off
iNest Innovation Ecosystem: the results of the spoke coordinated by UniTS presented to the public Read more about iNest Innovation Ecosystem: the results of the spoke coordinated by UniTS presented to the public Immagine Titolo (29).jpg Data notizia Thu, 11/12/2025 - 12:00 Categoria notizia University ateneo Research Destinatari canale University Destinatari target Business and Institutions Testo notizia The objective of iNEST (Interconnected North-East) Innovation Ecosystem Spoke 8, coordinated by the University of Trieste was the development of maritime, marine and inland water technologies and the creation of a Digital Twin of the Northern Adriatic Sea. The results were presented during the final event of the project funded by the National Recovery and Resilience Plan (NRRP). The event was organised at the San Giusto Castle in Trieste by UniTS and its partners, including the National Institute of Oceanography and Applied Geophysics (OGS), the Eastern-Adriatic-Sea Port Authority (PNAEAS) and the Andrea Galvani High-Adriatic Technology Hub (PTAA). ‘The activities of Spoke 8,’ stressed prof. Pierluigi Barbieri, iNEST coordinator at the University of Trieste ‘are inspired by European priorities and the ambitious programme called “Starfish Mission” aimed at knowing, protecting and restoring our waters by 2030. The mission sets out five general objectives: closing the knowledge gap, renewing governance related to the management of marine and coastal environments, regenerating marine and freshwater ecosystems, reaching zero pollution, decarbonising water. The theme of water management and the Blue Economy is taking on increasing economic, political and social interest and touches on multiple sectors, including transport, logistics, security, fisheries, tourism and underwater activities. The NRRP-funded initiative for research-based innovation brings contributions in terms of data acquisition systems, integration of information for sustainable management of coastal areas, technologies for adaptation to climate change’.The event called ‘Maritime, marine and inland water technologies: towards the Digital Twin of the Upper Adriatic’ was an opportunity to reflect on possible design developments. ‘Researchers from public bodies and innovators from companies in the North-Eastern and Southern Italy,’ explained prof. Pierluigi Barbieri ‘have developed data, models and products generated by specific activities and convergences between contiguous areas.’ Over €6 million funding was allocated to 24 research, development and innovation projects, with 53 beneficiaries, including 39 private bodies and 9 public research bodies from North-Eastern and Southern Italy. 34 small enterprises, 4 SMEs and 6 large enterprises were involved, supporting R&I and collaborative research in the thematic area of Spoke 8.’ The activities of Spoke 8 and those of the companies working with the University of Trieste have focused on applied research, not neglecting organisational, economic and legal aspects that regulate the transition to a more integrated and sustainable vision and management of the marine and aquatic environment in general. The digital transformation of companies operating in the Blue Economy sectors has been identified as a fundamental pillar of the smart specialisation strategy to support the competitiveness of SMEs operating in the iNEST ecosystem, favouring their conversion to new products and services with greater added value, increasing their degree of internationalisation.The five general objectives Biology of marine ecosystems The digitalisation of marine life has begun, including life that is still unexplored, thanks to tools capable of mapping physical and genetic aspects: the databases obtained open up new perspectives for innovative sectors, from biotechnology to sustainable fisheries and tourism. A living sea is a productive resource capable of generating value, wealth and future.Innovation in managing physical and chemical risks and their impact on the hydrosphere The Universities of Trieste, Trento and OGS are collaborating on a project that studies the chemical and acoustic risks of the sea, simulates extreme climatic events and analyses the effects of storm surges. Methods are also being developed to reduce the impact of wastewater and monitor pollutants, creating a digital twin to predict and manage environmental balance.Innovation in sustainable maritime transport A new means of tourist transport along the Trieste coast is being developed. Thanks to hybrid-electric propulsion, it can also be used for daily travel. Strategic routes have also been redefined and research infrastructures designed for a sustainable mobility system.Integrated land-sea maritime and space planning The research activity focuses on the coastal areas of North-Eastern Italy, in particular Friuli Venezia Giulia, characterised by the alternation of fresh and salt water, wetlands and dry areas. The project analyses these dynamics from an unexplored perspective: looking from sea to land, with an emphasis on sustainable and integrated mobility between sea, inland waters and land.A digital twin of the Upper Adriatic It is a virtual representation of a physical system that allows you to explore scenarios and obtain answers applicable to reality. The aim is to create a Digital Twin of the Northern Adriatic by integrating observations and models. By providing for the physical and biogeochemical properties of the marine ecosystem, this instrument will support both human activities and environmental protection. Abstract The investment worth over €6 million involved 53 beneficiaries, including 39 private bodies and 9 public research bodies from North-Eastern and Southern Italy. 34 small enterprises, 4 SMEs and 6 large enterprises involved to support R&I and collaborative research Documenti allegati Document Progetti finanziati iNEST Mostra nel diario Off
UniTS researchers create a Generative Artificial Intelligence assistant for the clinical management of Hepatitis C Read more about UniTS researchers create a Generative Artificial Intelligence assistant for the clinical management of Hepatitis C Immagine Titolo (31).jpg Data notizia Tue, 16/12/2025 - 12:00 Categoria notizia University ateneo Press releases Research Destinatari canale University Research Testo notizia Artificial intelligence capable of translating international guidelines for the treatment of hepatitis C into clear clinical responses consistent with the most up-to-date standards: this is the focus of an international study led by Mauro Giuffrè, PhD student at the University of Trieste (Department of Medicine, Surgery and Health Sciences) and researcher at the Yale University School of Medicine, validated by the same authors of the European guidelines for the treatment of the disease.Hepatitis C is an infection caused by HCV, which affects the liver and can develop into chronic forms with serious complications, such as cirrhosis and hepatocellular carcinoma. According to the World Health Organisation, around 58 million people worldwide live with chronic infection and there are over 1.5 million new cases each year. WHO has set an ambitious goal of eliminating hepatitis C as a public health threat by 2030, aiming to reduce new infections by 90% and deaths by 65%.The development of innovative tools based on artificial intelligence, such as that presented in the study by the University of Trieste, plays a key role in pursuing these objectives: Improving adherence to therapeutic guidelines and facilitating access to appropriate care even in contexts with limited resources are concrete steps that can contribute to achieving global targets.Significant improvements in clinical accuracyThe team developed and tested two innovative approaches to specialise GPT-4 in HCV management. On the one hand, they developed a retrieval-augmented generation (RAG) system that integrates European guidelines in real time which has been tested in two variants (RAG-Top1, which retrieves the single most relevant paragraph, and RAG-Top10, which retrieves the ten most relevant paragraphs). On the other hand, they developed a supervised fine-tuning (SFT) training of the language model on the guidelines’ contents.The results exceeded all expectations: compared to 36.6% of the GPT-4 base model, the RAG-Top10 model achieved an accuracy of 91.7% in expert evaluations, RAG-Top1 81.7% and the SFT model 71.7%, thus achieving significant improvements compared to the standard model.A novel validation system that includes guideline extenders and clinical expertsWhat makes this study particularly relevant is the applied validation methodology, a new entry in the scientific literature. Two separate groups of evaluators were recruited. The first group consisted of four expert hepatologists, selected from the lead authors and chairs of the HCV guidelines of the European Association for the Study of the Liver (EASL), the leading European experts in the treatment of hepatitis C and the drafters of the international guidelines.A second group of hepatologists was added from a tertiary reference centre (Humanitas Hospital, Rozzano), ensuring a double perspective of evaluation between guideline theorists and clinicalpractitioners in the field. This approach allowed us to obtain what the researchers themselves define as ‘an evaluation that approaches the gold standard in defining the accuracy of the outputs.’Towards responsible integration of AI in medicineThe findings open up concrete perspectives for the use of artificial intelligence in clinical decision support. Both RAG and SFT significantly improve the performance of Large Language Models (LLMs) in managing hepatitis C through guidelines, improving not only the accuracy and clarity of responses, but also the selection of therapeutic regimens in clinical scenarios. The study represents a significant step towards what the authors call ‘the safe integration of Generative Artificial Intelligence into clinical practice’, confirming the potential of specialised and expertly validated language models as concrete decision support tools in medicine, particularly valuable in highly complex contexts such as the management of chronic liver diseases. The research, presented in the article From Guidelines to Real-Time Conversation: Expert-Validated Retrieval-Augmented and Fine-Tuned GPT-4 for Hepatitis C Management, published on Liver International, was supported by Nicola Pugliese and Alessio Aghemo (Humanitas University), bioengineers from the University of Trieste Simone Kresevic and Milos Ajcevic (Department of Engineering and Architecture) and an international network of hepatologists and artificial intelligence specialists, including Dennis L. Shung (Yale), Francesco Negro (University Hospitals of Geneva), Massimo Puoti (Niguarda General Hospital; University of Milan Bicocca), Xavier Forns (Hospital Clínic Barcelona; IDIBAPS; CIBERehd) and Jean-Michel Pawlotsky (UPEC/INSERM; AP-HP Paul Brousse, Paris). Abstract The study coordinated by Mauro Giuffrè (DSM) saw the participation of the authors of the European guidelines for the treatment of the disease. Among the main authors, also Simone Kresevic and Milos Ajcevic (DIA UniTS), Nicola Pugliese and Alessio Aghemo (Humanitas University) Mostra nel diario Off Fotogallery
Allergy to Nickel: a UniTS – ASUGI published study Read more about Allergy to Nickel: a UniTS – ASUGI published study Immagine foto nickel.jpeg Data notizia Wed, 17/12/2025 - 12:00 Categoria notizia University ateneo Press releases Research Destinatari canale University Study Research Destinatari target Enroled students Graduates Testo notizia A study conducted by UniTS professors Luca Cegolon (also working at ASUGI Hygiene and Preventive Medicine Department) and Francesca Larese Filon (ASUGI Occupational Medicine Department) has just published in the international scientific journal Contact Dermatitis (Wiley). The researched was focused on contact allergy to 5% nickel sulfate in 31,948 patients who underwent patch tests in Triveneto from 1997 to 2023.Nickel is the most frequent cause of contact allergy, a hypersensitivity that can develop after repeated and prolonged skin exposures to allergens.In 1994, EU Directive 94/27/EC restricted the use of nickel in jewellery and other consumer products that may come into contact with human skin.Although this measure has led to a progressive reduction in nickel awareness in Europe, the benefit has mainly been seen in younger generations. Older people, on the other hand, who were sensitised before the entry into force of the Directive, contribute to the prevalence of nickel contact allergy at the global level.In detail, the geographical distribution of nickel awareness is heterogeneous and tends to be higher in Mediterranean countries than in Northern Europe, probably due to a late and less stringent application of the European Directive.Outside the European Union, specifically in North America and Japan, there continues to be a higher and increasing prevalence of nickel sensitisation over the years, due to the lack of restrictive legislation in this area.The University of Trieste study points out that the prevalence of nickel sensitisation was 26.1% during the study period (1997-2023), followed a progressively decreasing time trend and was significantly lower in males. The trend also revealed an inverted U-shaped trend with respect to the year of birth among women, falling from 35.70% in those born between 1955 and 1964 to 46.24% in those born between 1965 and 1974, to 41.36% among those born in 1975-1984.The inverted U-shaped pattern of positive reactions to patch tests by year of birth reflects nickel exposure and sensitisation in women aged 20 to 50 years, prior to the entry into force of the European Directive.As regards the work performed by the persons surveyed, there was a significantly higher prevalence of positive reactions to the patch test among traders, while it was lower among pensioners and housewives. A higher prevalence of positive reactions among traders could reflect prolonged exposure in professions involving coin manipulation, while age-related immunosenescence could explain the lower prevalence of sensitisation in pensioners and housewives.Although decreasing over the years, the prevalence of positive reactions to nickel has nevertheless remained higher than that of the northern European countries, probably due to a late and less rigorous application of the aforementioned European Directive. Other factors that may contribute to the higher prevalence of sensitisation in Mediterranean countries than in Northern Europe include social trends that have prompted Italian women to use nickel-containing jewellery products early, and higher ambient temperatures that facilitate the release and penetration of allergens into human skin from nickel-containing products. Abstract Luca Cegolon and Francesca Larese Filon conducted a study involving about 32,000 Triveneto patients between 1997 and 2023 Documenti allegati Document Graphical Abstract Mostra nel diario Off
Homecoming 2025 UniTS Alumni’s success stories to inspire today's students, tomorrow's professionals Read more about Homecoming 2025 UniTS Alumni’s success stories to inspire today's students, tomorrow's professionals Immagine WhatsApp Image 2025-12-11 at 13.04.11.jpeg Data notizia Thu, 11/12/2025 - 12:00 Categoria notizia University Press releases University and society Destinatari canale University Destinatari target Enroled students Graduates Business and Institutions Society Testo notizia The event organised by the Career Service of the University of Trieste was held this evening (Wednesday 10th December 2025), Homecoming – Success stories from UniTS and Alumni Happy Hour (aperitivo con gli alumni), to inspire new members and students who have already started their university careers and to foster mutual exchange, strengthening a link between those who are still attending the University and those who have not abandoned it, despite having finished their studies. THE GUESTS AND THE PROGRAMME – Four UniTS Alumni - now established professionals in different sectors - Andrea Cozzi (responsible for the New Exploration Initiatives and General Manager of Eni in Lebanon), Chiara Pacella (lead of the Language Management and Localization Quality Program teams of Meta), Silvia Toffolutti (Global Diversity and Inclusion and Wellbeing Lead of Chiesi) and Diego Scapolan (Project Manager of Allianz) moderated by Cristina Perini, head of the Press Office of the University of Trieste and graduated in Communication Sciences, shared their different experiences, from online dissemination to a job in multinational companies, in as many different stories, united from the same starting point: the University of Trieste. The event was held at the former Military Hospital of Trieste, the historic building of Via Fabio Severo, which has been housing the new Student Residence Hall since last September as the result of an agreement between the University of Trieste and ARDiS. ‘The University of Trieste is part of a unique ecosystem of knowledge, in an area where there are important research centres. It is a university that tests you, that also teaches you to accept failure and get up. I also had to repeat tests, in one case I gave myself a ‘failed’ on my own. In my university career, failures have been moments of growth’, stressed the Magnificent Rector Prof. Donata Vianelli in her opening speech, pointing out how the stories of those who have passed through those same university classrooms can help those who attend them today in facing a passage that is not without challenges, in the context of a labour market in which there are fewer and fewer clear and predefined paths and more and more careers to be built with vision and courage. The Rector addressed a direct invitation to those present: ‘Choose paths that fascinate you both at university and at work’.During the first part of the evening, ‘UniTS Success Stories’, hosted in the Sala Cappella, the five Alumni spoke to the audience of UniTS students, researchers, teachers and administrative staff describing their own personal, often original, path, which led them from graduation to the construction of a solid career.ALUMNI – Andrea Cozzi, graduate in Geology, is now in charge of the New Exploration Initiatives and General Manager of Eni in Lebanon, explained how from a path initially bent towards academic teaching he has converted to the search for oil. From his university experience, he recalled the great spirit of collaboration and closeness between students, elements that also accompanied him in subsequent professional challenges in complex international contexts.On the other hand, Chiara Pacella, via video link from Dublin, spoke about the transition from the local university dimension to work in a large international reality such as Meta: a graduate in Interpreting and Translation, today Pacella is Lead of the company’s Language Management team and Localization Quality Program, and she recommended that students seize all international opportunities to engage with other contexts and broaden their perspectives, starting with Erasmus. Her work focuses on the cultural adaptation of digital products, integrating language skills and technological tools in a hybrid model between human contribution and new technologies. When talking about her education in Trieste, she stressed the ‘very solid and high-level foundations’, fully comparable to those experienced in other contexts, albeit within a challenging and ‘severe’ path.Silvia Toffolutti, on the other hand, deals with human resources. After graduating in Philosophy, she completed an MBA in Organisation and Personnel Management at Bocconi University in Milan and today she is Global Diversity and Inclusion and Wellbeing Lead at the Chiesi Group. In her speech, she illustrated projects dedicated to diversity and inclusion, with a particular focus on gender equality and the inclusion of people with disabilities, including the monitoring of gender pay gaps, company policies related to parenting and the promotion of women’s leadership. From her philosophy studies she said that she had brought at work the dialectical approach, the curiosity and the desire to question consolidated points of view: fundamental qualities to innovate also within organisations.Last but not least, Diego Scapolan, graduated in Business Administration & Administrative and Professional Consulting, now Project Manager at Allianz. Scapolan advised the students not to be frightened by challenges, but to embrace them with enthusiasm and ‘a pinch of unconsciousness’, he suggested to cultivate a mentality of continuous learning, indispensable today more than ever to face the needs of a rapidly changing society and, therefore, the labour market. He recalled the role of talent management to understand the skills that will be required in the future and called for ‘seeing the stars but aiming for the moon’, without forgetting one’s loved ones and passions – such as sport – that should not be sacrificed for work. He also suggested using experiences such as Erasmus to see what is outside and compare with other realities.The knowledge and exchange continued at the end of the talk with a networking aperitif where students and PhD students had the opportunity to discuss directly with teachers and alumni, in a relaxed context that helped to strengthen the sense of belonging to a community that UniTS wants to enhance. A network from which opportunities and collaborations can be generated, in the spirit of the Alumni project. Mentors also took part in the event: professionals with at least five years of work experience in various fields, graduates of the University of Trieste, members of the Mentors4UniTS initiative, thanks to which the University supports students enrolled in the penultimate or final year of a master’s degree course to achieve a growth path. The comparison with mentors helps them to focus their professional goals and enhance their attitudes: after some online meetings, tomorrow, Thursday 11th December 2025, the mentors will meet in person the students assigned to them.THE EVENT IN SHORT – Homecoming – UniTS Success Stories is an annual event dedicated to students now at its seventh edition: today’s students, currently enrolled at the University of Trieste, and yesterday’students, the Alumni who bring their experience through inspiring talks, encouraging encounter and dialogue. The aim of the initiative is to tell success stories of graduates of the University of Trieste who, thanks to the skills acquired during their university career, have built significant careers in different professional fields, helping to strengthen the reputation and prestige of the University, which has gained two positions in the 2025-2026 Censis ranking of Italian Universities, thus reaching 5th place among medium-sized universities (between 10,000 and 20,000 students); this result – which is accompanied by an increase of more than 13% in new enrolments for undergraduate degree courses compared to last year – is due, among other factors, to the employability of graduates and the quality of the facilities, and events such as Homecoming - UniTS Success Stories and Alumni Happy Hour want to help make these fact well known. Abstract Four successful alumni brought their first-hand experience to inspire and help young people in the delicate transition from university to work Mostra nel diario Off